A recent warning from the FDA indicates infants and toddlers under 2 years old are particularly vulnerable to developing Methemoglobinemia if exposed to Benzocaine.
Methemoglobinemia is a rare disorder of the blood that limits the blood’s ability to carry oxygen. It can occur as an acquired disease and as an inherited disease. The inherited version of the disease can have mild consequence for some up to severe and life threatening consequences for others, depending on the type. Families with the inherited version are generally well versed in the prognosis of their type of Methemoglobinemia.
The acquired version of the disease is generally less dramatic and easily managed once the triggering agent is identified and avoided. It is, however, very frightening and stressful when it develops and warrants an immediate trip to the doctor. On rare occasion this type has also been life threatening.
Benzocaine is a known trigger for this disease and the FDA has issued a warning regarding use for children under age 2. They are significantly more susceptible and vulnerable to a more severe reaction. The soothing agents for teething and other mouth sores like canker sores and viral ulcers typically contain Benzocaine. This warning is particularly important for parents of toddlers and their dentists. Some typical agents containing Benzocaine are: Anbesol, Hurricaine, Orajel, Baby Orajel, Orabase, and store brands. Many of the dentist’s topical anesthetics contain Benzocaine.
Also common sense reminds us, topical anesthetics have not been available until very recent human history. Infants get through their teething issues with good nurturing, good food, and friendly things to chew on.
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